Pertactin Is Required for Bordetella Species To Resist Neutrophil-Mediated Clearance
نویسندگان
چکیده
منابع مشابه
Pertactin is required for Bordetella species to resist neutrophil-mediated clearance.
Pertactin (PRN) is an autotransporter protein produced by all members of the Bordetella bronchiseptica cluster, which includes B. pertussis, B. parapertussis, and B. bronchiseptica. It is a primary component of acellular pertussis vaccines, and anti-PRN antibody titers correlate with protection. In vitro studies have suggested that PRN functions as an adhesin and that an RGD motif located in th...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2010
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.00188-10